ABSTRACT
We report the case of a young Chhattisgarhi male with polymorphic dermosporidiosis (cutaneous rhinosporidiosis). He had multiple subcutaneous nodules and an ecthymatoid skin lesion along with nasal rhinosporidiosis. The diagnosis was confirmed by demonstration of sporangia with endospores in fine-needle aspiration cytology (FNAC), histopathology, and imprint smear from the skin lesions. Treatment was by surgical excision, electrocoagulation, and dapsone. There was no recurrence. Dermatologists should be aware of the diverse cutaneous manifestations of this primarily nasal disease. This is the second published report of polymorphic dermosporidiosis, and the first one reporting an ecthymatoid lesion.
Subject(s)
Adult , Animals , Humans , Leg/pathology , Male , Nose Diseases/parasitology , Rhinosporidiosis/pathology , Rhinosporidium/isolation & purification , Skin/pathology , Skin Diseases, Parasitic/pathology , Ulcer/parasitologyABSTRACT
Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days duration. The eruption stopped abruptly at the midline of the torso, completely sparing the right side of the body. The lesions were arranged in whorls and streaks corresponding to the lines of Blaschko. Skin biopsy showed hyperkeratosis and features suggestive of sub-acute spongiotic dermatitis with lymphocytic infiltrate around the blood vessels in the dermis. Patient was diagnosed as a case of Blaschkoid dermatitis. To the best of our knowledge, this is the first case of this condition being reported from India.
Subject(s)
Adult , Biopsy , Cyproheptadine/therapeutic use , Dermatitis/drug therapy , Dermatologic Agents/therapeutic use , Glucocorticoids/therapeutic use , Histamine H1 Antagonists/therapeutic use , Humans , Hydrocortisone/analogs & derivatives , Keratosis/pathology , Lymphocytes/pathology , Male , Prednisolone/therapeutic use , Skin/pathology , Skin Diseases, Papulosquamous/drug therapyABSTRACT
Two cases of Ehlers-Danlos syndrome affecting two real brothers are being reported. Both of them presented with features of atrophy and hyperextensibility of skin, hypermobility of joints and scarring at the sites of trauma. The elder brother also had kyphoscoliosis and hypogonadism with testicular failure.
Subject(s)
Adolescent , Ehlers-Danlos Syndrome/diagnosis , Follow-Up Studies , Genetic Predisposition to Disease , Hand Deformities, Congenital/diagnosis , Humans , Hypogonadism/diagnosis , Kyphosis/diagnosis , Male , Risk Assessment , Severity of Illness Index , SiblingsABSTRACT
A twenty-year-old man with borderline tuberculoid leprosy with lesion on the penile shaft is reported. The lesion was detected when the patient developed an upgrading reaction after MDT. The diagnosis was confirmed by histopathology. Leprosy lesions are uncommonly reported on the penis and interestingly, some seem to have been detected during reactional episodes only. It appears that like facial lesions, genital patches may also be more prone to develop a type 1 reaction.
ABSTRACT
Cicatricial pemphigoid (CP) occurring in a 60-year-old male is described. He had involvement of conjunctival, nasal and oral mucosae, in addition to skin lesions. Diagnosis was confirmed by histopathology. He responded well to oral steroids and dapsone. However, vision in one eye was lost.
ABSTRACT
Mucormycosis is the name for invasive fungal infection caused by mucorales. The disease is uncommon and produces serious and rapidly fatal infection in patients with serious pre-existing illness. The classical presentation of rhinocerebral mucormycosis is involvement of nasal mucosa with invasion of paranasal sinuses and orbit. We report a case of mucormycosis in an otherwise healthy female who had developed acute renal failure following gastroenteritis.
Subject(s)
Adult , Anti-Bacterial Agents/therapeutic use , Central Nervous System Infections/etiology , Fatal Outcome , Female , Gastroenteritis/complications , Humans , Immunocompetence , Acute Kidney Injury/complications , Mucormycosis/diagnosis , Nose/pathologyABSTRACT
One hundred and twenty nine newly registered cases of pauci-bacillary leprosy were put on Dapsone daily and Rifampicin once a month and were followed up for one year. Out of 129 cases, 108 (83.7%) were found to be clinically active at the end of one year of multidrug treatment (MDT). In 25 out of these 108 cases, skin biopsy was done and well defined granulomas were seen after therapy in 11 patients (44%).